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Ultra Brahmi - Promoting mental clarity & concentration - Backed by Clinical Research

Ultra Brahmi - Promoting mental clarity & concentration - Backed by Clinical Research

$30.00 NZD
$30.00 NZD
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About the herb : Brahmi (Bacopa monnieri) has been traditionally used by yogis and practitioners of Ayurvedic medicine for its potential cognitive and mental benefits. In Ayurveda, Brahmi is considered a powerful herb for promoting mental clarity, concentration, and enhancing spiritual awareness.

It contains active compounds, such as bacosides, which are believed to enhance brain function and have a positive impact on the nervous system, helping to promote a sense of calmness and relaxation. As a result, it is often used as a natural nootropic or brain-boosting supplement. 

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Why is this Brahmi Special?

As there are many verities of Brahmi and also many different extraction processes, the quality of Brahmi can significantly vary. 

So, to find the most potent Brahmi, the team at Amulya Research Center tried all forms of traditional Brahmi extracts but were unsatisfied with their efficacies.

Hence the adept team of Doctors at the Amulya Research Center created a Proprietary way of Growing, Cultivating, and Processing Bacopa Monnieri (Brahmi) into Ultra Brahmi Capsules which retain the highest quantity of Bacosides and other lesser-known actives.

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The Science:

Active Compounds in Brahmi - Brahmi (bacopa) contains bacoside A & B, Sterols, Alkaloids, and Polyphenols.

Bacoside A, B are the major constituents present in the Bacopa Monnieiri (Brahmi) plant in the form of saponins.

Apart from Hersaponin, apigenin, D-mannitol, monnierasides I-III, plantainoside B and cucurbitacin; the alkaloids brahmine, herpestine and nicotine have also been classified in the chemical constituents of Bacopa monnierai (Brahmi).



BENEFITS OF BRAHMI
ACCORDING TO CLINICAL RESEARCH


Improves Memory & Prevents Memory Loss

​In a double-blind, randomized, placebo-controlled trial of 35 subjects aged above 55 years using the Wechsler Memory Scale, there was a significant improvement in total memory score of patients administered Bacopa monnieri (Brahmi), seen after 8 weeks.

 

Helpful to ADHD patients

In a double-blind, randomized, placebo-controlled trial of 36 children with Attention Deficit Hyperactivity Disorder, the symptom scores for restlessness were reduced in 93% of children on taking Bacopa Monnieri (Brahmi). Furthermore,  improvement in self-control was observed in 89% of the children. The attention-deficit symptoms were reduced in 85% of them.

 

Aids in Treatment of Alzheimer's and Schizophrenia

Cognitive deficit observed in rats receiving PCP were given Bacopa Monnieri (Brahmi). Interestingly, receiving Brahmi (bacopa)  before PCP administration can restore this cognitive deficit by decreasing NMDAR1 in the effected brain areas. Therefore, Bacopa Monnieri (Brahmi) could be a novel neuroprotective agent for the prevention of cognitive deficit in schizophrenia and Alzheimer's.

 

Powerful Antioxidant & Anti-inflammatory agent

A study on rat brains suggested that Bacopa monnieri (Brahmi) exhibits a significant antioxidant effect after sub-chronic administration, which extends to the hippocampus as well. The results suggest that the increase in oxidative free radical scavenging activity by Bacopa Monnieri may explain the cognition-facilitating action of Bacopa Monnieri (Brahmi).


Helps Reduce Episodes of Seizures

​In a study conducted by E.Komali, rats were induced with seizures and then given Bacopa monnieri (Brahmi) as the anti-epileptic treatment. The results showed that Bacopa Monnieri (Brahmi) extracts caused perceptible changes in the cholinergic system, and the Cholinesterase activities started returning to the control levels, suggesting that selected Bacopa Monnieri(Brahmi) extracts offer neuroprotection by ameliorating the cholinergic activity during induced epilepsy.

 

Enhances Retention of New Information

​Besides cognitive improvement, Bacopa Monnieri (Brahmi) can also enhance learning capability. Consumption of Bacopa monnieri for 3 months in 76 human subjects between 40 and 65 years of age in the University of Wollongong, Australia resulted in significant effects on retention of new information.

 

Reduces Cortisol Levels

​In a study conducted by Micheli, it was found that Bacopa monnieri(Brahmi)  significantly reduced cortisol, cytokines, and artemin LPS-dependent alterations in plasma, while increasing the brain-derived neurotrophic factor levels.

 

Research References

  • Usha Pinakin Dave, PhD; Sunila Rajeev Dingankar, MA; Vinod Swaroop Saxena, MD; Joshua Allan Joseph, MVSc; Bharathi Bethapudi, MVSc; Amit Agarwal, PhD; Venkateshwarlu Kudiganti, MD, 2014, An Open-label Study to Elucidate the Effects of Standardized Bacopa monnieri Extract in the Management of Symptoms of Attention-deficit Hyperactivity Disorder in Children

  • Raghav S, Singh H, Dalal PK, Srivastava JS, Asthana OP: (2006) Randomized controlled trial of standardized Bacopa monniera extract in age- associated memory impairment.

  • Radbul manap et al. (2019). bacopa monnieri, a Neuroprotective Lead in Alzheimer Disease: A Review on Its Properties, Mechanisms of Action, and Preclinical and Clinical Studies. htt

  • S. K. Bhattacharya, A. Bhattacharya, A. Kumar, and S. Ghosal,“ (2000) Antioxidant activity of Bacopa monniera in rat frontal cortex, striatum and hippocampus,” Phytotherapy Research.

  • Piyabhan P, Wetchateng T. Neuroprotective effects of Bacopa monnieri (Brahmi) on novel object recognition and NMDAR1 immunodensity in the prefrontal cortex, striatum and hippocampus of sub-chronic phencyclidine rat model of schizophrenia. Journal of the Medical Association of Thailand = Chotmaihet Thangphaet. 2014 Aug;97 Suppl 8:S50-5. PMID: 25518293.

  • Micheli, L, Spitoni, S, Di Cesare Mannelli, L, Bilia, AR, Ghelardini, C, Pallanti, S. Bacopa monnieri as augmentation therapy in the treatment of anhedonia, preclinical and clinical evaluation. Phytotherapy Research. 2020; 34: 2331– 2340. https://doi.org/10.1002/ptr.6684

  • Chaudhari (2017), Neurocognitive Effect of Nootropic Drug Brahmi (bacopa monnieri) in Alzheimer's Disease.

  • Prabhakar, S., Saraf, M. K., Pandhi, P., and Anand, A. (2008). Bacopa monniera exerts antiamnesic effect on diazepam-induced anterograde amnesia in mice.

  • Roodenrys, S., Booth, D., Bulzomi, S. et al. Chronic Effects of Brahmi (Bacopa monnieri) on Human Memory. Neuropsychopharmacol 27, 279–281 (2002). https://doi.org/10.1016/S0893-133X(01)00419-5

  • Banerjee, S., Anand, U., Ghosh, S., Ray, D., Ray, P., Nandy, S., Deshmukh, G. D., Tripathi, V., & Dey, A. (2021). Bacosides from Bacopa monnieri extract: An overview of the effects on neurological disorders. Phytotherapy Research, 35( 10), 5668– 5679. https://doi.org/10.1002/ptr.7203

  • Nimisha Pulikkal Sukumaran, Augustine Amalraj, Sreeraj Gopi, Neuropharmacological and cognitive effects of Bacopa monnieri (L.) Wettst – A review on its mechanistic aspects, Complementary Therapies in Medicine, Volume 44, 2019, Pages 68-82, ISSN 0965-2299, https://doi.org/10.1016/j.ctim.2019.03.016 (https://www.sciencedirect.com/science/article/pii/S0965229919301736)

  • Smith, Eric, Helen M. Palethorpe, Yoko Tomita, Jinxin V. Pei, Amanda R. Townsend, Timothy J. Price, Joanne P. Young, Andrea J. Yool, and Jennifer E. Hardingham 2018. "The Purified Extract from the Medicinal Plant Bacopa monnieri, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and Apoptosis" Cells 7, no. 7: 81. https://doi.org/10.3390/cells7070081

  • Chuenjid Kongkeaw, Piyameth Dilokthornsakul, Phurit Thanarangsarit, Nanteetip Limpeanchob, C. Norman Scholfield, Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract, Journal of Ethnopharmacology, Volume 151, Issue 1, 2014, Pages 528-535, ISSN 0378-8741, https://doi.org/10.1016/j.jep.2013.11.008 (https://www.sciencedirect.com/science/article/pii/S0378874113008027)

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